Cell Symposia: Using Stem Cells to Model and Treat Human Disease

Speaker

Christine Mummery, Leiden University Medical Centre, The Netherlands

Christine MummeryChristine is Professor of Developmental Biology at Leiden University Medical Centre, The Netherlands and she is chair of the Department of Anatomy and Embryology.  Her research has largely concerned mouse cardiovascular  development and the role of growth factors. Over the last 10 years this has extended to the directed differentiation of mouse and human embryonic stem cells to cardiomyocytes and vascular cells. She pioneered studies characterizing cardiomyocytes from hES cells and was among the first to inject them in mouse heart and assess their effect on myocardial infarction. Her more recent work has concerned creating cardiac and vascular disease models based on induced pluripotent stem cells and their potential use in drug safety pharmacology and drug discovery.
She has recently written a popular book on stem cells “Stem Cells: scientific facts and Fiction” (2011) intended as a semi-lay guide to stem cell biology and applications. She is also the founding editor in chief of Stem Cell Reports, the new journal of the ISSCR,  editorial board member of Cell Stem Cells and Stem Cells and past president of the International Society of Differentiation (2010-2012). In 2010 she was elected as a member of the Royal Netherlands Academy of Arts and Science.  In the same year she became a member of the board of the academy. She was recently awarded an ERC Advanced grant to continue research on cardiovascular derivatives of human pluripotent stem cells and their use as disease models.

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