Cell Symposia: Using Stem Cells to Model and Treat Human Disease

Program

(subject to change)

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Thursday, November 21, 2013
13:30–15:45 Registration
15.45–16.00 Welcome and Introduction
16:00–16:45 Opening Keynote: George Q. Daley, Boston Children's Hospital, Harvard Medical School
Modeling Genetic Blood Disease with iPS Cells
Session I: Modeling disease using stem cells I
Chair: Kevin Eggan
16:45–17:15 Clive Svendsen, Cedars-Sinai Regenerative Medicine Institute
Using iPS cells to both model and treat motor neuron diseases
17:15–17:30 Fabian Zanella, University of California, San Diego
iPS cell models to uncover mechanisms underlying varying clinical symptoms associated with Arrhythmogenic Cardiomyopathy
17:30–18.00 Refreshment Break
18.00–18:30 Fred H Gage, Salk Institute
Lineage specific differentiation into functionally defined neurons
18:30–19:00 Lorenz Studer, Memorial Sloan-Kettering Cancer Center
Induced aging for iPSC-based modeling of late-onset disease
19:15–20:15 Drinks Reception
Friday, November 22, 2013
Session II: Modeling disease using stem cells II
Chair: George Q. Daley
9:00-9.30 Chad Cowan, Harvard Stem Cell Institute, Harvard University
Genome editing to generate human cellular disease models
9:30–9:45 Brian T.D. Tobe, Sanford-Burnham Medical Research Institute
Use of hiPSCs to uncover a novel developmentally-based target of therapeutic lithium in bipolar disease
9:45–10:15 Christine Mummery, Leiden University Medical Centre
Pluripotent stem cells: the new heart patient
10:15–10:45 Refreshment Break
10:45–11:15 Steve Goldman, University of Rochester
Human glial progenitor-cell based treatment and modeling of neurological disease
11:15–11:45 Kevin Eggan, Harvard University
Using stem cells to dissect the population architecture of complex neurological disease: a case study in ALS
11:45-12:00 Poster teasers
12:00-13:00 Lunch
13:00-15:00 Poster session I
Session III – Organogenesis/in vivo reprogramming
Chair: Amy Wagers
15:00–15:30 Deepak Srivastava, Gladstone Institute
Reprogramming Approaches for Cardiovascular Disease
15:30–16:00 Janet Rossant, Hospital for Sick Children
Lung epithelial progenitors and differentiated airway cells from embryonic stem cells- progress and pitfalls
16:00–16:15 Yang Xu, University of California, San Diego
New strategies to induce immune tolerance of hESC-derived allografts
16:15-16:45 Refreshment Break
16:45–17:00 Karine Rizzoti, MRC/National Institute for Medical Research
Mobilized adult pituitary stem cells contribute to endocrine regeneration in response to physiological demand
17:00–17:15 Madeline Lancaster, Institute of Molecular Biotechnology
Modeling human brain development and disease in cerebral organoids
17:15–17:45 Juan Carlos Izpisua Belmonte, Salk Institute
Driving heart repair by promoting a regeneration-competent state
17:55-18:45 Meet the Editor Workshop (Q & A session with Cell Press editor Christina Lilliehook)
19.00 "Meet the Speakers Dinner" (ticket holders only )
Saturday, November 23, 2013
Session IV – Screening stem cells
Chair: Lorenz Studer
8:30 - 9:00 Leonard I. Zon, Boston Children's Hospital, Harvard Medical School
Finding suppressors of disease-associated phenotypes using a cross-species comparison of tissue production from stem cells
9:00–9:30 Peter G. Schultz, Scripps Research Institute
A Chemical Approach to Stem Cell Biology
9:30-9:45 Susanne Höing, Max Planck Institute for Molecular Biomedicine
Stem cell-based phenotypic screening identifies a novel kinase inhibitor that protects motor neurons from stress-induced degeneration
9:45–10:15 Refreshment Break
10:15–10:45 Amy J. Wagers, Harvard University, Joslin Diabetes Center
Using stem cells to discover pathways that regulate repair and malignancy in skeletal muscle
Session V – Stem cells in clinical trials
Chair: Clive Svendsen
10:45-11:15 Nobuko Uchida, StemCells Inc.
Biology and Translation of Human Neural Stem Cells, HuCNS-SC
11:15–11:45 Eduardo Marbán, Cedars-Sinai Regenerative Medicine Institute
Therapeutic regeneration of the injured human heart
11:45-12:00 Poster teasers
12:00-13:00 Lunch
13:00-15:00 Poster session II
15:00 - 15:30 Daniel R. Marshak, PerkinElmer
Mesenchymal Stem Cells in Clinical Translation
15:30–17:00 Panel on Overcoming Barriers for Translation of Stem Cell research
Alan Trounson – Need for understanding the underlying mechanism of response to cell  based therapies in clinical trials
Leonard I. Zon – Translational research with stem cells: the path to the clinic
Sally Temple – TBD
Fred H Gage – TBD
17:00–17:30 Refreshment Break
17.30–18:15 Closing Keynote: Sally Temple, Neural Stem Cell Institute
The CNS Frontier:  Stem Cell-based Therapeutics for Retinal Disease
  Closing remarks

 

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